Dr George Sharbeen

Elucidating the mechanism by which MutY-Homolog knockdown kills pancreatic cancer cells


Elucidating the mechanism by which MutY-Homolog knockdown kills pancreatic cancer cells


2015 "Woolies on Wheels" Innovation Grant


Pancreatic Cancer Translational Research Group, Lowy Cancer Research Centre, UNSW Australia

Principal Investigator

Dr George Sharbeen, Post-Doctoral Research Fellow - University of New South Wales

Time required to complete project

1 year

Project Summary

Pancreatic cancer is a deadly disease that urgently requires better treatments. Dr. Sharbeen and his team have identified a protein that, when inhibited, can kill pancreatic cancer cells and decrease their resistance to cancer drugs. This project will identify the mechanism(s) behind these effects. This information will help translate their target into the clinic.

Dr George Sharbeen with Associate Professor Phoebe Phillips

Research Reports
Click to download progress reporting on the outcomes of this research.

‘Woolies on Wheels’ Innovation Grants

The Avner Pancreatic Cancer Foundation's four "Woolies on Wheels" have been made possible by the efforts of the Woolworths business leaders who cycled the 2014 ‘Woolies on Wheels’ charity cycle to raise funds in support of Avner Pancreatic Cancer Foundation. The grants will support $100,000 in seed funding for innovative Pancreatic Cancer projects with a desire to increase interest and investment in pancreatic cancer research.

The objectives of the ‘Woolies on Wheels’ Innovation grants are to:

  • Support established scientists and/or early career researchers to develop preliminary data necessary to support pursuit of additional funding in subsequent years.
  • Encourage and retain talented skilled individuals in the field of pancreatic cancer.

Emphasis will be given to support novel approaches examples of which would include immunotherapy.