Project Title: Therapeutically targeting a solute carrier transporter in the stroma of pancreatic cancer
Grant: Innovation Grant 2016
Institution: University of New South Wales
Principal Investigator: Associate Professor Phoebe Phillips
Position Held: Head, Pancreatic Cancer Translational Research Group and Associate Professor, University of New South Wales (Appointed 2011). National Health and Medical Research Council (NHMRC) Career Development Fellow (Appointed 2012-2016). Executive Director, Australian Society for Medical Research (ASMR) (since 2013; immediate Past-President).
Time required to complete project: 1 year
Project Summary: Pancreatic cancer (PC) claims five Australian lives daily, with little improvement in patient survival in 40 years. Targeting PC cells alone has failed. Pancreatic tumours are surrounded by extensive scar tissue, which inhibits drug delivery and increases tumour growth. Our novel nanomedicine may be a therapy to breakdown this scar.